WHAT CAUSES: Cold intolerance, Loss of appetite, Low blood pressure, Aversion to food or drink & nausea?

my mother has those symptons. what could they all mean. she takes alot of meds. like 10 - 20. i know she takes 9 different blood pressure meds. could it be overdose? side effects of meds? combining medication complication? or a illness. she has heart disease. & recently underwent a kidney stent for kidney failure. the effects of kidney failure, seem to have subsided. but now her body's gone nuts.